- Etude en double aveugle versus placebo considérant les effets d’une supplémentation en RIAA/Acacia sur l’homéostasie de l’insuline. (September 2011)
Etude en double aveugle versus placebo considérant les effets d’une supplémentation en RIAA/Acacia sur l’homéostasie de l’insuline.
Robert H. Lerman, MD, PhD, Matthew L. Tripp, PhD, and Jeffrey S. Bland, PhD.
“Double-Blind, Placebo-Controlled Trial Examining the Effects of RIAA/Acacia Supplementation on Insulin Homeostasis”
Functional Medical Research CenterSM, the clinical arm of Metagenics, Inc., Gig Harbor, WA.
- Une alimentation de type méditerranéen à faible charge glycémique améliore les paramètres du syndrome métabolique chez la femme, l’ajout d’un aliment fonctionnel riche en phytonutriments augmente les bénéfices sur le métabolisme des lipoprotéines. (January 2011)
Une alimentation de type méditerranéen à faible charge glycémique améliore les paramètres du syndrome métabolique chez la femme, l’ajout d’un aliment fonctionnel riche en phytonutriments augmente les bénéfices sur le métabolisme des lipoprotéines.
J L. Jones, M L. Fernandez, M S. McIntosh, W Najm, M C. Calle, C Kalynych, C Vukich, J Barona, D Ackermann, J Eun Kim, V Kumar, M Lott, J S. Volek, R H. Lerman,
« A Mediterranean-style low-glycemic-load diet improves variables of metabolic syndrome in women, and addition of a phytochemical-rich medical food enhances benefits on lipoprotein metabolism »
Journal of Clinical Lipidology 5, 188–196, 2011
- META060 inhibits osteoclastogenesis and MMPs in vitro, and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis. (March 2010)
Veera R. Konda, Anuradha Desai, Gary Darland, Jeffrey S. Bland, Matthew L. Tripp. META060 inhibits osteoclastogenesis and MMPs in vitro, and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis. Arthritis Rheum. 2010 Mar 3. [Epub ahead of print]. PMID: 20201075. laetitia
- Les extraits phytochimiques d’Acacia et de Houblon diminuent la lipotoxicité dans des adipocytes 3T3-L1, chez des souris db/db et chez des personnes présentant un syndrome métabolique. (January 2010)
Les extraits phytochimiques d’Acacia et de Houblon diminuent la lipotoxicité dans des adipocytes 3T3-L1, chez des souris db/db et chez des personnes présentant un syndrome métabolique.
Minich DM, Lerman RH, Darland G, Babish JG, Pacioretty LM, Bland JS, Tripp ML.
“Hop and Acacia Phytochemicals Decreased Lipotoxicity in 3T3-L1 Adipocytes, db/db Mice, and Individuals with Metabolic Syndrome.”
J Nutr Metab.2010;2010. pii: 467316.
- Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins. (January 2010)
Robert H. Lerman, Deanna M. Minich, Gary Darland, Joseph J. Lamb, Jyh-Lurn Chang, Alex Hsi, Jeffrey S. Bland, Matthew L. Tripp. Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins. Journal of Clinical Lipidology. 2010;4:59-68.
- Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial. (January 2010)
Michael F. Holick, Joseph J. Lamb, Robert H. Lerman, Veera R. Konda, Gary Darland, Deanna M. Minich, Anuradha Desai, Tai C. Chen, Melissa Austin, Jacob Kornberg, Jyh-Lurn Chang, Alex Hsi, Jeffrey S. Bland, Matthew L. Tripp. Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial. J Bone Miner Metab. 2010 28(3):342-50. PMID: 20024591.
- Rho-iso-alpha acids and tetrahydro-iso-alpha acids are selective protein kinase inhibitors which potently reduce inflammation in macrophages in vitro and in the collagen-induced rheumatoid arthritis model in vivo. (December 2009)
Matthew L. Tripp, Veera R. Konda, Gary Darland, Anuradha Desai, Jyh-Lurn Chang, Brian J. Carroll, Jeffrey S. Bland. Rho-iso-alpha acids and tetrahydro-iso-alpha acids are selective protein kinase inhibitors which potently reduce inflammation in macrophages in vitro and in the collagen-induced rheumatoid arthritis model in vivo. Acta Hort. (ISHS) 848:221-234.
- Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins. (November 2009)
Robert H. Lerman, Deanna M. Minich, Gary Darland, Joseph J. Lamb, Jyh-Lurn Chang, Alex Hsi, Jeffrey S. Bland, Matthew L. Tripp. Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins. Journal of Clinical Lipidology 2010;4:59-68..
- Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation. (August 2009)
Veera R. Konda, Anuradha Desai, Gary Darland, Jeffrey S. Bland, Matthew L. Tripp. Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation. J Inflamm. 2009 Aug 27;6:26.PMID: 19712471.
- A science-based, clinically tested dietary approach for the metabolic syndrome. (June 2009)
Barbara Schiltz, Deanna M. Minich, Robert H. Lerman, Joseph J. Lamb, Matthew L. Tripp, Jeffrey S. Bland. A science-based, clinically tested dietary approach for the metabolic syndrome. Metab Syndr Relat Disord 2009 Jun;7(3):187-92. PMID: 19450142
- L’enrichissement d’une alimentation de type méditerranéen à faible charge glycémique par des nutriments spécifiques améliore les facteurs de risque cardiométabolique chez des patients présentant un syndrome métabolique et une hypercholestérolémie, dans un (November 2008)
Robert H. Lerman, Deanna M. Minich, Gary Darland, Joseph J. Lamb, Barbara Schiltz, John G. Babish, Jeffrey S. Bland, Matthew L. Tripp. Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial. Nutr Metab (Lond) 2008:5(1):29. PMID: 18983673
- META060 inhibits multiple kinases in the NF-kB pathway and suppresses LPS-mediated inflammation in vitro and ex vivo. (November 2008)
Anuradha Desai, Veera R. Konda, Gary Darland, Melissa B. Austin, Kudlapura S. Prabhu, Jeffrey S. Bland, Brian J. Carroll, Matthew L. Tripp. META060 inhibits multiple kinases in the NF-kB pathway and suppresses LPS-mediated inflammation in vitro and ex vivo. Inflamm Res. 2008;1-6. PMID: 19169645
- Dietary management of the metabolic syndrome beyond macronutrients. (August 2008)
Deanna M. Minich, Jeffrey S. Bland. Dietary management of the metabolic syndrome beyond macronutrients. Nutrition Reviews 2008;66(8):429-444. PMID: 18667004
- Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops. (May 2008)
Amy J. Hall, John G. Babish, Gary Darland, Brian J. Carroll, Veera R. Konda, Robert H. Lerman, Jeffrey S. Bland, Matthew L. Tripp. Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops. Phytochemistry 2008;69(7):1534-1547. PMID: 18358504
- Clinical safety and efficacy of NG440: a novel combination of rhoiso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions. (September 2007)
Deanna M. Minich, Jeffrey S. Bland, Jeffrey J. Katke, Gary Darland, Amy J. Hall, Robert H. Lerman, Joseph J. Lamb, Brian J. Carroll, Matthew L. Tripp. Clinical safety and efficacy of NG440: a novel combination of rhoiso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions. Can J Physiol Pharmacol. 2007;85:872-883. PMID: 18066133
- Acid–Alkaline Balance: Role in Chronic Disease and Detoxification. (August 2007)
Deanna M. Minich, Jeffrey S. Bland. Acid–Alkaline Balance: Role in Chronic Disease and Detoxification. Altern Ther Health Med. 2007 Jul-Aug; 13(4):62-65.
- A review of the clinical efficacy and safety of cruciferous vegetable phytochemicals. (June 2007)
Deanna M. Minich, Jeffrey S. Bland. A review of the clinical efficacy and safety of cruciferous vegetable phytochemicals. Nutrition Reviews. 2007;65:259-267. PMID: 17605302
- Comparison of anti-inflammatory activity of two selective kinase response modulators (SKRMs), rhoiso-alpha acids (RIAA) and tetrahydro-iso-alpha acids (THIAA), in lipopolysaccharide (LPS) mediated inflammation in RAW 264.7 macrophages. (June 2007)
Anuradha Desai, Veera R. Konda, Amy J. Hall, Jeffrey S. Bland, Matthew L. Tripp. Comparison of anti-inflammatory activity of two selective kinase response modulators (SKRMs), rhoiso-alpha acids (RIAA) and tetrahydro-iso-alpha acids (THIAA), in lipopolysaccharide (LPS) mediated inflammation in RAW 264.7 macrophages. The FASEB Journal. 2007;21:702. 5.
- Can indole-3-carbinol-induced changes in cervical intraepithelial neoplasia be extrapolated to other food components? (October 2006)
Karen J. Auborn. Can indole-3-carbinol-induced changes in cervical intraepithelial neoplasia be extrapolated to other food components? J Nutr 2006;136(10):S2676-S78. PMID: 16988146
- Toxicology and pharmacology of rhoiso-alpha acids (RIAA), hop-derived inhibitors of prostaglandin E2 formation. (June 2006)
Bhaskar R. Shenai, Gary K. Darland, Robert H. Lerman, Matthew L. Tripp, Jeffrey S. Bland. Toxicology and pharmacology of rhoiso-alpha acids (RIAA), hop-derived inhibitors of prostaglandin E2 formation. Experimental Biology meeting abstracts. The FASEB Journal: 2006;20:A1145.
- Editorial commentary: evaluation of the article published in JAMA (295:58-64, 2006) by Schulman et al. Review of arginine and vascular health study (June 2006)
Louis J. Ignarro, Jeffrey S. Bland. Editorial commentary: evaluation of the article published in JAMA (295:58-64, 2006) by Schulman et al. Review of arginine and vascular health study. JANA Volume 9, No. 2, 2006.
- Anti-inflammatory mechanism of rhoiso-alpha acids from hop extract. (June 2006)
Veera R. Konda, Amy J. Hall, Anuradha Desai, Brian J. Carroll, Gary Darland, Jeff S. Bland , Matthew L. Tripp. Anti-inflammatory mechanism of rhoiso-alpha acids from hop extract. 2006 Experimental Biology meeting abstracts. The FASEB Journal: 2006;20:A1145.
- Rho iso-alpha acids, a modified hop (Humulus lupulus) extract, inhibits protein kinases involved in autoimmune disease. (June 2006)
Matthew L. Tripp, Veera R. Konda, Amy J. Hall, Anuradha Desai, Brian J. Carroll, Gary K. Darland, Robert H. Lerman, Dennis A. Emma, Jeffrey S. Bland. Rho iso-alpha acids, a modified hop (Humulus lupulus) extract, inhibits protein kinases involved in autoimmune disease. 2006 Experimental Biology meeting abstracts. The FASEB Journal: 2006;20:A1125.
- Effet d’un régime à faible index glycémique, à base de protéines de soja et phytostérols, sur les facteurs de risque cardiovasculaires chez des femmes ménopausées. (February 2006)
Daniel O. Lukaczer, DeAnn J. Liska, Robert H. Lerman, Gary Darland, Barbara Schiltz, Matthew L. Tripp, Jeffrey S. Bland. Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in postmenopausal women. Nutrition. 2006;22(2):104-13. PMID: 16459222
- A pilot trial evaluating Meta050, a proprietary combination of reduced iso-alpha acids, rosemary extract, and oleanolic acid in patients with arthritis and fibromyalgia. (October 2005)
Daniel O. Lukaczer, Gary Darland, Matthew L. Tripp, DeAnn J. Liska, Robert H. Lerman, Barbara Schiltz, Jeffrey S. Bland. A pilot trial evaluating Meta050, a proprietary combination of reduced iso-alpha acids, rosemary extract, and oleanolic acid in patients with arthritis and fibromyalgia. Phytotherapy Research. 2005;19:864-69. PMID: 16261517
- Beneficial effects of a low-glycemic-index diet with soy protein and phytosterols on inflammation and cardiovascular risk factors in postmenopausal women. (June 2005)
DeAnn J. Liska, Matthew L. Tripp, Daniel O. Lukaczer, Robert H. Lerman, Barbara Schiltz, Jeffrey S. Bland. Beneficial effects of a low-glycemic-index diet with soy protein and phytosterols on inflammation and cardiovascular risk factors in postmenopausal women. 2005 Experimental Biology meeting abstracts. The FASEB Journal.
- Randomized cross-over study of RIAA, rosemary extract, and oleanolic acid on gastrointestinal integrity using fecal Calprotectin. (June 2005)
DeAnn J. Liska, Matthew L. Tripp, Daniel O. Lukaczer, Robert H. Lerman, Gary Darland, Barbara Schiltz, Jeffrey S. Bland. Randomized cross-over study of RIAA, rosemary extract, and oleanolic acid on gastrointestinal integrity using fecal Calprotectin. 2005 Experimental Biology meeting abstracts. The FASEB Journal: .
- Hop and modified hop extracts have potent in vitro anti-inflammatory properties. (June 2005)
Matthew L. Tripp, Gary Darland, Daniel O. Lukaczer, Jeffrey S. Bland. Hop and modified hop extracts have potent in vitro anti-inflammatory properties. Published Proceedings from 1st International Symposium on Humulus. Editors K.E. Hummer and J.A. Henning Acta Horiculturae 668, ISHS 2005.
- Functional medicine pioneer. (September 2004)
Jeffrey S. Bland. Functional medicine pioneer. Altern Ther Health Med. 2004;10:74-81. PMID: 15478789
- Benefits of a proprietary reduced iso-alpha acids (hops), rosemary extract, and oleanolic acid supplement on pain in subjects with osteoarthritis. (June 2004)
Daniel O. Lukaczer, Robert H. Lerman, Gary Darland, DeAnn J. Liska, Barbara Schiltz, Matthew L. Tripp, Jeffrey S. Bland. Benefits of a proprietary reduced iso-alpha acids (hops), rosemary extract, and oleanolic acid supplement on pain in subjects with osteoarthritis. 2004 Experimental Biology meeting abstracts. The FASEB Journal.
- Assessment of bone resorption in osteoarthritic subjects using a proprietary reduced iso-alpha acids, rosemary extract, and oleanolic acid supplement. (June 2004)
Robert H. Lerman, Daniel O. Lukaczer, Gary Darland, DeAnn J. Liska, Barbara Schiltz, Matthew L. Tripp, Jeffrey S. Bland. Assessment of bone resorption in osteoarthritic subjects using a proprietary reduced iso-alpha acids, rosemary extract, and oleanolic acid supplement. 2004 Experimental Biology meeting abstracts. The FASEB Journal.
- Initial observations of a controlled trial comparing a soy and phytosterol beverage and dietary program with the American Heart Association (AHA) Step 1 dietary program. (June 2004)
Daniel O. Lukaczer, Robert H. Lerman, DeAnn J. Liska, Barbara Schiltz, Jeffrey S. Bland. Initial observations of a controlled trial comparing a soy and phytosterol beverage and dietary program with the American Heart Association (AHA) Step 1 dietary program. 2004 Experimental Biology meeting abstracts. The FASEB Journal.
- Etude Clinique ex vivo de l’activité anti-inflammatoire d’un mélange déposé aux propriétés synergétiques d’extrait de houblon, romarin et acide oléanolique. (January 2003)
Etude Clinique ex vivo de l’activité anti-inflammatoire d’un mélange déposé aux propriétés synergétiques d’extrait de houblon, romarin et acide oléanolique.
Robert Lerman, John Babish, Dan Lukaczer, Gary Darland, Matthew Tripp, Barbara Schiltz, DeAnn Liska, Terrance Howell, and Jeffrey S. Bland
“Ex Vivo Clinical Study of the Anti-Inflammatory Activity of a Proprietary Synergistic Blend of Hops Extract, Rosemary, and Oleanolic Acid “
Advanced Nutrition Publications, Inc. 2003
